Prof Themba Ginindza

Person

Prof Themba Ginindza

Telephone

+27 (031) 260 4214

Email

Ginindza@ukzn.ac.za

Campus

Howard College

Designation

Epidemiologist & Senior Lecturer

Research Interests

  • Cancer Epidemiology and Cancer prevention research: mainly HPV-related cancers, Lung cancer, Multiple Myelomas cancer, Paediatric cancers, HIV-related cancers.
  • Rationalization of HPV-related cancers screening in the Era of HIV and HPV/EBV infections.
  • Development of standardized, programmatic approach to cancer screening and the appropriate use of screening technologies.
  • Mapping & Modelling of Communicable and Non-communicable diseases with a focus on cancers related to HIV and HPV infections.
  • Economical cost associate with Cancer
  • Cancer Therapy Innovation/Precision Medicine

Biosketch

Prof Themba Ginindza is an experienced Epidemiologist who has conducted research across diverse disease spectrum, covering STIs (HPV, HIV/AIDS, CT, NG, TV, Syphilis), Sexually Reproductive Health (SRH) and Cancer Epidemiology. He also teaches and supervises epidemiological research at postgraduate level. Currently, he is the Lead PI in the Multinational Lung Cancer Control Programme (MLCCP) involving Kenya, South Africa, Tanzania, Eswatini, and more recently Lesotho and Ethiopia. He is Co-PI in the Cervical cancer Screening and Treatment algorithms study using HPV testing in Africa (CESTA) in South Africa. He has collaborated on many multidisciplinary projects in South Africa and beyond, including an ongoing HPV vaccine roll-out in Eswatini and Cervical Cancer Elimination research project. He led the Burden of HPV infection and HPV-related conditions among sexually active women in the Kingdom of ESwatini: its implications during the era of HIV epidemic research. He worked on a Clinical Trial on Cervical cancer Screening and Treatment algorithms study using HPV testing in Africa in KZN. Additionally, he developed the South African Rotavirus surveillance system; previously worked in planning, monitoring and evaluation of HIV/AIDS programmes, coordination of HIV/AIDS research projects in ESwatini and South Africa, managing and analysing hospital mining data for monitoring admissions and out-patients related to Influenza and pneumonia infections. Finally, he has an international working experience in countries like Malawi, Philippines, Kingdom of ESwatini and Finland.

Publications:

1. Mbeje NP, Ginindza TG, Jafta N. Establishing and Evaluating Cancer Surveillance System in KwaZulu-Natal, South
Africa. Cancer Informatics (2021); 20: 1–11. https://doi.org/10.1177/11769351211029967
2. Motlana MKTN, Ginindza TG, Mitku AA, Jafta N. Spatial Distribution of Cancer Cases Seen in Three Major Public
Hospitals in KwaZulu-Natal, South Africa. Cancer Informatics (2021); 20: 1–12.
https://doi.org/10.1177%2F11769351211028194
3. Zibako P, Hlongwa M, Tsikai N, Manyame S, Ginindza TG. Mapping evidence on management of cervical cancer
in sub-Saharan Africa: scoping review protocol. BMC Systematic Reviews (2021); 10:180.
https://doi.org/10.1186/s13643-021-01740-3
4. GBD 2021 Local Burden of Disease HIV Collaborators** (Ginindza TG). Subnational mapping of HIV incidence
and mortality among individuals aged 15–49 years in sub-Saharan Africa, 2000–18: a modelling study. Lancet
HIV (2021); 8: e363–75. https://doi.org/10.1016/S2352-3018(21)00051-5
5. Lubuzo B, Hlongwana K, Ginindza T. Cancer care reform in South Africa: A case for cancer care coordination: A
narrative review. Palliative and Supportive Care Journal; 19 (2),1–9.
https://doi.org/10.1017/S1478951521000432
6. Ngcamphalala C, Sartorius B, Östensson E, Ginindza TG. The economic burden of cervical cancer in Eswatini:
Societal perspective. PLOS One Journal (2021), https://doi.org/10.1371/journal.pone.0250113
7. Ngcamphalala C, Ostensson E, Hlongwa M, Ginindza TG. Mapping evidence on the distribution of the costs
associated with cancer of prostate, cervix, and female breast in the sub-Saharan Africa: protocol for a scoping
review. BMC Systematic Reviews (2021) 0:113, https://doi.org/10.1186/s13643-021-01672-y
8. Mncwabe N, Hlongwana KW, Ginindza TG. An ethnographic study exploring the experiences of patients living
with cancer illness in support group settings in KwaZulu-Natal, South Africa. Afr J Prm Health Care Fam Med.
(2021);13(1), a2303. https://doi.org/10.4102/phcfm.v13i1.2303
9. Mlaba PC, Ginindza TG, Hlongwana K. Family Caregivers’ Perspectives of the Economic Burden Imposed through
Caring for Family Members with Cancer in KwaZulu-Natal, South Africa. Southern African Journal of Social
Work and Social Development (2020) 32 (3):13 pages. https://doi.org/10.25159/2708-9355/7099.
10. Nwagbara UI, Ginindza TG, Hlongwana KW. Lung cancer awareness and palliative care interventions
implemented in low-and middle-income countries: a scoping review. BMC Public Health (2020) 20:1466.
https://doi.org/10.1186/s12889-020-09561-0
11. Kahere M, Ginindza TG. The burden of non-specific chronic low back pain among adults in KwaZulu-Natal, South
Africa: a protocol for a mixed-methods study. BMJ Open (2020); https://doi:10.1136/bmjopen-2020-039554.
https://bmjopen.bmj.com/content/bmjopen/10/9/e039554.full.pdf
12. Chola M., Hlongwana K., Ginindza T.G. Patterns, trends, and factors associated with contraceptive use among
adolescent girls in Zambia (1996 to 2014): a multilevel analysis. BMC Women’s Health (2020) 20:185
https://doi.org/10.1186/s12905-020-01050-1
13. Murray CJL & GBD 2019 Risk Factors Collaborators* (Ginindza TG). Global burden of 87 risk factors in 204
countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The
Lancet (2020); 396: 1223–49.
14. GBD 2019 Universal Health Coverage Collaborators* (Ginindza TG). Measuring UHC effective coverage index in
204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019.
The Lancet (2020). https://doi.org/10.1016/S0140-6736(20)30750-9
15.Mathias CT, Mianda S, Ginindza TG. Facilitating factors and barriers to accessibility and utilization of kangaroo
mother care service among parents of low birth weight infants in Mangochi District, Malawi: A Qualitative study.
BMC Pediatrics (2020) 20:355. https://doi.org/10.1186/s12887-020-02251-1
16. Hlongwana K, Lubuzo B, Phindile Mlaba, Zondo S, Ginindza TG. Multistakeholder Experiences of Providing,
Receiving, and Setting Priorities for Lung Cancer Care in KwaZulu-Natal Province, South Africa. JCO Global
Oncol 2020:25. American Society of Clinical Oncology, DOI: 10.1200/GO.20.21000.
https://ascopubs.org/doi/pdf/10.1200/GO.20.21000
17.Wiens KE, Lindstedt PA, Blacker BF, Local Burden of Disease Diarrhoea Collaborators* (Ginindza TG). Mapping
geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries,
2000–17. The Lancet Global Health (2020)8(8): e1038-e1060. https://doi: 10.1016/S2214-109X(20)30230-8.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30230-8/fulltext
18. Reiner RC, Local Burden of Disease Diarrhoea Collaborators*(Ginindza TG). Mapping geographical inequalities
in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17. Lancet Glob
Health 2020; 8: e1038–60. doi: https://doi.org/10.1016/S2214-109X(20)30230-8
19. Lekoane KMB, Kuupiel D, Mashamba-Thompson TP, Ginindza TG. The interplay of HIV and human
papillomavirus-related cancers in sub-Saharan Africa: scoping review. BMC: Systematic Reviews (2020)
9:88. https://doi.org/10.1186/s13643-020-01354-1
20. Kahere M, Ginindza TG. Mapping evidence on the prevalence, incidence, risk factors and cost associated with
chronic low back pain among adults in Sub-Saharan Africa: a systematic scoping review protocol. BMC
Systematic Reviews (2020) 9:57 https://doi.org/10.1186/s13643-020-01321-w
21. Nwagbara UI, Ginindza TG, Hlongwana KW. Health systems influence on the pathways of care for lung cancer
in low- and middle-income countries: a scoping review. Globalization and Health (2020) 16:23
https://doi.org/10.1186/s12992-020-00553-8
22. Buhle Lubuzo, Ginindza TG, Hlongwana K. The barriers to initiating lung cancer care in low-and middle-income
countries. Pan African Medical Journal. 2020; 35:38. doi: 10.11604/pamj.2020.35.38.17333.
http://www.panafrican-med-journal.com/content/article/35/38/full/
23. Ndlovu SR., Kuupiel D., Ginindza TG: Mapping evidence on the distribution of Paediatric cancers in subSaharan Africa: a scoping review protocol. BMC Systematic Reviews Vol.8, No. 262 (2019):
https://doi.org/10.1186/s13643-019-1184-4
24. Lubuzo B, Ginindza T, Hlongwana K. Exploring barriers to lung cancer patient access, diagnosis, referral and
treatment in Kwazulu-Natal, South Africa: the health providers’ perspectives: TLCR journal; Vol 8, No 4 (2019)
http://tlcr.amegroups.com/article/view/31039/21998
25. Fitzmaurice Christina, GBD-Cancer Collaboration (Ginindza TG). Global, Regional, and National Cancer
Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-Years for 29
Cancer Groups, 1990 to 2017 A Systematic Analysis for the Global Burden of Disease Study, JAMA Oncol.
doi:10.1001/jamaoncol.2019.2996.
https://jamanetwork.com/journals/jamaoncology/fullarticle/2752381?utm_campaign=articlePDF%26utm_mediu
m%3darticlePDFlink%26utm_source%3darticlePDF%26utm_content%3djamaoncol.2019.2996
26. GBD 2017 HIV collaborators (Ginindza TG). Global, regional, and national incidence, prevalence, and mortality
of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global
Burden of Diseases, Injuries, and Risk Factors Study 2017. The Lancet HIV (2019).
https://doi.org/10.1016/S2352-3018(19)30196-1
27. Dlamini SB, Sartorius B, Ginindza T. Mapping the evidence on interventions to raise awareness on lung cancer
in resource poor settings: a scoping review protocol: BMC Systematic Reviews; vol. 8, No: 217 (2019)
https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1138-x
28. Lekoane BKM, Mashamba-Thompson TP, Ginindza TG. Evidence on the prevalence, incidence, mortality and
trends of human papilloma virus-associated cancers in sub-Saharan Africa: systematic scoping review. BMC
Cancer; vol 19, No: 563 (2019). https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5781-3
29. Chola M, Hlongwana K, Ginindza TG: Mapping Evidence on Decision-Making on Contraceptive Use Among
Adolescents: A Scoping Review Protocol. Systematic Reviews 2018: 7:201:
https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-018-0881-8
30. Ginindza TG, Almonte M, Dlamin X, Sartorius B. Distribution of cervical abnormalities detected by visual
inspection with acetic acid in Swaziland, 2011–2014: A retrospective study Afr J Prm Health Care Fam Med.
2018;10(1), a1773. https://phcfm.org/index.php/phcfm/article/view/1773/2856
31. Ginindza TG, Sartorius B., Projected cervical Cancer incidence in Swaziland using three methods and local
survey estimates BMC Cancer 2018 18:639. https://doi.org/10.1186/s12885-018-4540-1
32. Mathias CT, Mianda S, Ginindza TG ., Evidence of the factors that influence the utilization of Kangaroo Mother
Care by parents with low birth weight infants in Low and Middle-Income Countries (LMICs): A scoping review
protocol. BMC Systematic Reviews (2018)
33. Lekoane BKM, Mashamba-Thompson TP, Ginindza TG., Mapping evidence on the distribution of human
papillomavirus-related cancers in sub-Saharan Africa: scoping review protocol BMC Systematic Reviews
(2017) 6:229, DOI 10.1186/s13643-017-0623-3.
https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-017-0623-3
34. Ginindza TG, Dlamini X, Sartorius B, Östensson E. Cost analysis of Human Papillomavirus-related cervical
diseases and genital warts in Swaziland PLOS One Journal (2017),
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177762
35. Ginindza TG, Stefan CD, Tsoka-Gwegweni JM, Dlamini X, Jolly PE; Weiderpass E, Broutet N; Sartorius B.
Prevalence and risk factors associated with sexually transmitted infections (STIs) among women of reproductive
age in Swaziland. BMC-Infectious Agents and Cancer (2017) 12:29 DOI 10.1186/s13027-017-0140-y.
http://infectagentscancer.biomedcentral.com/articles/10.1186/s13027-017-0140-y
36. Ginindza TG, Dlamini X, Almonte M, Herrero R, Jolly P, Tsoka-Gwegweni JM, Weiderpass E, Broutet N,
Sartorius B. Prevalence of and Associated Risk Factors for High Risk Human Papillomavirus among Sexually
Active Women, Swaziland. PLOS One Journal (2017),
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170189
37. Okwali M, Greenlee H, Ginindza T, Jolly P, Akinyemiju TF. Adherence to cancer prevention guidelines in South
Africa is associated with health care access. Int Health. 2015 Jul 20. pii: ihv044.
38. R. Zachariah, B.Mwagomba, D.Misinde, B.C.Mandere, A.Bemeyani, T. Ginindza, H.Cortier,
K.Bissel,A.Jahnh,A.D.Harries. Vital registration in rural Africa:Is there a way forward to report on health targets
of the Millennium Development Goals? Transactions of the Royal Society of Tropical Medicine and
Hygiene (2011). http://www.sciencedirect.com/science/article/pii/S0035920311000435
39. Kalichman S.C., Simbayi L.C, Cloete A, Mthembu P.P, Mkhonta R.N, Ginindza T. Measuring AIDS stigmas in
people living with HIV/AIDS: the Internalized AIDS-Related Stigma Scale. AIDS Care Journal, Volume 2121
Issue 1 January 2009 , pages 87 – 93
http://www.informaworld.com/smpp/title~db=all~content=t713403300~tab=issueslist~branches=21 – v2121
40. Maphalala G, Okello V, Mndzebele S, Gwebu P, Mulima N, Dlamini S, Nhlabatsi B, Ginindza T., et al (2008).
Surveillance of transmitted HIV drug resistance in the Manzini-Mbabane Corridor, Swaziland, in 2006, Antiviral
Therapy Volume 13, 2008; Supplement 2: 95–100
https://www.intmedpress.com/serveFile.cfm?sUID=11e26356-4a74-4757-8ceb-80c02b08f520
41. Whiteside, A., Ginindza, T.G., Parikh A., Andrade, C., Lisa Arrehag, L., Dlamini, S. (2006). The Socio-Economic
Impact of HIV/AIDS in Swaziland, http://www.gametlibrary.worldbank.org/FILES/1619 Socioeconomic%20Impact%20of%20AIDS%20-%20Swaziland.pdf