Prof Themba Ginindza

Person

Prof Themba Ginindza

Telephone

+27 (031) 260 4214

Email

Ginindza@ukzn.ac.za

Campus

Howard College

Designation

Epidemiologist & Senior Lecturer

Research Interests

  • Cancer Epidemiology and Cancer prevention research: mainly HPV-related cancers, Lung cancer, Multiple Myelomas cancer, Paediatric cancers, HIV-related cancers.
  • Rationalization of HPV-related cancers screening in the Era of HIV and HPV/EBV infections.
  • Development of standardised, programmatic approach to cancer screening and the appropriate use of screening technologies.
  • Mapping & Modelling of Communicable and Non-communicable diseases with a focus on cancers related to HIV and HPV infections.
  • Economical cost associate with Cancer
  • Cancer Therapy Innovation/Precision Medicine

Biosketch

Prof Themba G. Ginindza is the Director of the Cancer & Infectious Diseases Epidemiology Research Unit (CIDERU). He is an experienced Epidemiologist who has conducted research across diverse disease spectrum, covering STIs (HPV, HIV/AIDS, CT, NG, TV, Syphilis), and cancer Epidemiology, culminating in over 60 publications in peer-reviewed international and local journals, more than half of which are in Quintile One (Q1) Ranking. He also teaches Epidemiology and supervises epidemiological research at postgraduate level Currently, Lead PI in Multinational Lung Cancer Control Programme (MLCCP) involving Kenya, South Africa, Tanzania, Eswatini, Lesotho and Ethiopia (2017 – 2023); PI in Cervical Cancer Prevention, Access and Control (CCPAC) Programme in Zululand District, KwaZulu-Natal, through a Consortium of Health Systems Trust (HST), Genius Quality (GQ), Department of Health (DOH) and Cancer and Infectious Diseases Epidemiology Research Unit (CIDERU) (2022 – 2024); Co-PI in the Cervical cancer Screening and Treatment algorithms study using HPV testing in Africa (CESTA) in South Africa a consortium involving UKZN, WHO, IARC ) (2019 – 2022); Co-PI in Dual Screening by Spectral Artificial Visual Examination (SAVE) for Female Genital Schistosomiasis (FGS) and cervical cancer (DUAL-SAVE-FGS), a consortium involving UKZN, Durban University of Technology (DUT) and Centre for Bilharzia and Tropical Health Research (CBTHR) (South Africa), Universidade Eduardo Mondlane (Mozambique), University of Eswatini (Eswatini), University of Copenhagen (Denmark), Universitetet iAgder and Oslo University (Norway), QCELL IKE (Greece) (2022 – 2025) and Co-PI in Healthcare Professionals’ Compassion Fatigue and Associated Effects of Caring for Patients with COVID-19 in Selected Hospitals in Durban and Mthatha, South Africa (2022 – 2024).

He is Member of the UK Research and Innovation (UKRI) International Development Peer Review College, BMC Women’s Health Journal Peer Reviewer and Global Burden of Diseases Collaborator. Additionally, member of the Expert Writing group for Palliative Care National Guideline, National Department of Health, South Africa. He member of the Expert writing Group for the National Lung cancer Screening guidelines, National Department of Health for South Africa. Also collaborated on many multidisciplinary projects in South Africa and beyond, including an ongoing HPV vaccine roll-out in Eswatini and Cervical Cancer Elimination research project. He led the Burden of HPV infection and HPV-related conditions among sexually active women in the Kingdom of ESwatini: its implications during the era of HIV epidemic research (Lead PI). He worked on a Clinical Trial on Cervical cancer Screening and Treatment algorithms study using HPV testing in Africa in KZN as Co-PI. Additionally, he developed the South African Rotavirus surveillance system; previously worked in planning, monitoring and evaluation of HIV/AIDS programmes, coordination of HIV/AIDS research projects in ESwatini and South Africa, managing and analysing hospital mining data for monitoring admissions and out-patients related to Influenza and pneumonia infections. Finally, he has an international working experience in countries like Malawi, Philippines, Kingdom of ESwatini and Finland.

Publications:

  1. Mbeje, N.P, Ginindza, T, Jafta, N. Epidemiological Study of Risk Factors for Lung Cancer in KwaZulu‐Natal, South Africa. J. Environ. Res. Public Health (2022), 19, 6752. https://doi.org/10.3390/ijerph19116752
  2. Kahere M, Ginindza TG. A cross-sectional hospital-based study of correlates of disability in patients with chronic low back pain in KwaZulu-Natal, South Africa. BMC Musculoskeletal Disorders (2021) 23:438. https://doi.org/10.1186/s12891-022-05397-4
  3. Ngcamphalala, C., Östensson, E. & Ginindza, T.G. The economic burden of prostate cancer in Eswatini. BMC Health Serv Res 22, 483 (2022). https://doi.org/10.1186/s12913-022-07817-6
  4. Dodzo RC, Ogunsakin RE, Ginindza T. Prevalence and Associated Risk Factors for Anaemia Among Pregnant Women Attending Ante-Natal Clinic, Eswatini. Afr J Prm Health Care Fam Med. (2022), (vol: 14, #1), a3339, https://doi.org/10.4102/phcfm.v14i1.3339
  5. Ndlovu SR, Hlongwa M, Ginindza TG. Mapping Evidence on the Risk Factors Associated with Paediatric Cancers in Sub-Saharan Africa: A Scoping Review. BMC Systematic Reviews (2022), https://doi.org/10.1186/s13643-022-01931-6
  6. Kahere M, Hlongwa M, Ginindza TG. A scoping review on the epidemiology of chronic low back pain among adults in Sub-Saharan Africa. J. Environ. Res. Public Health (IJERPH) (2022), 19, 2964. https://doi.org/10.3390/ijerph19052964
  7. Ogunsakin RE, Oluwakemi E, Ginindza T. A bibliometric analysis of the literature on Norovirus disease from 1991-2021. J. Environ. Res. Public Health (IJERPH) (2022), 19, 2508. https://doi.org/10.3390/ijerph19052508
  8. Lubuzo B, Hlongwana KW, Ginindza T. Improving timely access to diagnostic and treatment services for lung cancer patients in KwaZulu-Natal, South Africa: priority-setting through nominal group techniques. J. Environ. Res. Public Health (2022), 19(4), 1918, https://doi.org/10.3390/ijerph19041918
  9. Kahere M, Ginindza TG, The prevalence and psychosocial risk factors of chronic low back pain in KwaZulu-Natal. Afr J Prm Health Care Fam Med. (2022), Vol-14(1), a3134, https://doi.org/10.4102/phcfm.v14i1.3134
  10. Zondo S, Ginindza TG, Hlongwana K. The extrinsic factors affecting patient access, referral and treatment of lung cancer in selected oncology public health facilities in KwaZulu-Natal: HLS (2022), vol-10:10170 https://doi.org/10.4081/hls.2022.10170
  11. Achoki T, GBD collaborators (Ginindza TG). Health trends, inequalities, and opportunities in South Africa’s provinces, 1990–2019: Findings from the Global Burden of Disease 2019 Study. J Epidemiol Community Health (2022), 0:1–11: http://dx.doi.org/10.1136/jech-2021-217480
  12. Alvarez E, GBD 2019 Adolescent and Young Adult Cancer Collaborators* (Ginindza TG). The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Oncol (2022), https://doi.org/10.1016/S1470-2045(21)00581-7
  13. Kocarnik JM, GBD 2019 Cancer Collaboration, Ginindza TG. Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019. JAMA Oncol (2021), https://doi:10.1001/jamaoncol.2021.6987
  14. Zibako P, Tsikai N, Manyame S, Ginindza TG. Knowledge, attitude and practice towards cervical cancer prevention among mothers of girls aged between 9 and 14 years: a cross sectional survey in Zimbabwe. BMC Women’s Health (2021), 21:426. https://doi.org/10.1186/s12905-021-01575-z
  15. Kahere M, Ginindza TG. The prevalence and risk factors of chronic low back pain among adults in KwaZulu-Natal, South Africa: an observational cross-sectional hospital-based study. BMC Musculoskeletal Disorders (2021) 22:955; https://doi.org/10.1186/s12891-021-04790-9
  16. Mlaba PC, Ginindza TG, Hlongwana K. The social burden experienced by families caring for members living with cancer in KwaZulu-Natal, South Africa. Afr J Prm Health Care Fam Med. (2021), 13(1), https://doi.org/10.4102/phcfm.v13i1.2955
  17. Mathias CT, Mianda S, Ohdihambo JN, Hlongwa M, Singo-Chipofya A, Ginindza TG. Facilitating factors and barriers to kangaroo mother care utilisation in low- and middle-income countries: A scoping review. Afr J Prm Health Care Fam (2021);13(1). https://doi.org/10.4102/phcfm.v13i1.2856
  18. Kgakge K, Hlongwa M, Ginindza T. The distribution of work-related musculoskeletal disorders among nurses in sub-Saharan Africa: a scoping review protocol. BMC Systematic Reviews (2021), 10:229. https://doi.org/10.1186/s13643-021-01774-7
  19. Mbeje NP, Ginindza TG, Jafta N. Establishing and Evaluating Cancer Surveillance System in KwaZulu-Natal, South Africa. Cancer Informatics (2021), 20: 1–11. https://doi.org/10.1177/11769351211029967
  20. Motlana MKTN, Ginindza TG, Mitku AA, Jafta N. Spatial Distribution of Cancer Cases Seen in Three Major Public Hospitals in KwaZulu-Natal, South Africa. Cancer Informatics (2021); 20: 1–12. https://doi.org/10.1177/11769351211028194
  21. Zibako P, Hlongwa M, Tsikai N, Manyame S, Ginindza TG. Mapping evidence on management of cervical cancer in sub-Saharan Africa: scoping review protocol. BMC Systematic Reviews (2021); 10:180. https://doi.org/10.1186/s13643-021-01740-3
  22. Sartorius B., GBD 2021 Local Burden of Disease HIV Collaborators** (Ginindza TG). Subnational mapping of HIV incidence and mortality among individuals aged 15–49 years in sub-Saharan Africa, 2000–18: a modelling study. Lancet HIV (2021), 8: e363–75. https://doi.org/10.1016/S2352-3018(21)00051-5
  23. Jahagirdar D., GBD 2019 HIV Collaborators* (Ginindza TG). Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: The Global Burden of Diseases Study 2019. Lancet HIV 2021; 8: e633–51. https://doi.org/10.1016/S2352-3018(21)00152-1
  24. Lubuzo B, Hlongwana K, Ginindza T. Cancer care reform in South Africa: A case for cancer care coordination: A narrative review. Palliative and Supportive Care Journal (2021); 19 (2),1–9. https://doi.org/10.1017/S1478951521000432
  25. Ngcamphalala C, Östensson E, Ginindza TG. The economic burden of cervical cancer in Eswatini: Societal perspective.  PLOS One Journal (2021), https://doi.org/10.1371/journal.pone.0250113
  26. Ngcamphalala C, Ostensson E, Hlongwa M, Ginindza TG. Mapping evidence on the distribution of the costs associated with cancer of prostate, cervix, and female breast in the sub-Saharan Africa: protocol for a scoping review. BMC Systematic Reviews (2021) 0:113, https://doi.org/10.1186/s13643-021-01672-y
  27. Mncwabe N, Hlongwana KW, Ginindza TG. An ethnographic study exploring the experiences of patients living with cancer illness in support group settings in KwaZulu-Natal, South Africa. Afr J Prm Health Care Fam Med. (2021);13(1). https://doi.org/10.4102/phcfm.v13i1.2303
  28. Mlaba PC, Ginindza TG, Hlongwana K. Family Caregivers’ Perspectives of the Economic Burden Imposed through Caring for Family Members with Cancer in KwaZulu-Natal, South Africa. Southern African Journal of Social Work and Social Development (2020) 32 (3):13 pages. https://doi.org/10.25159/2708-9355/7099.
  29. Nwagbara UI, Ginindza TG, Hlongwana KW. Lung cancer awareness and palliative care interventions implemented in low-and middle-income countries: a scoping review. BMC Public Health (2020) 20:1466. https://doi.org/10.1186/s12889-020-09561-0
  30. Kahere M, Ginindza TG. The burden of non-specific chronic low back pain among adults in KwaZulu-Natal, South Africa: a protocol for a mixed-methods study. BMJ Open (2020); https://doi:10.1136/bmjopen-2020-039554 .
  31. Chola M., Hlongwana K., Ginindza T.G. Patterns, trends, and factors associated with contraceptive use among adolescent girls in Zambia (1996 to 2014): a multilevel analysis. BMC Women’s Health (2020) 20:185 https://doi.org/10.1186/s12905-020-01050-1
  32. Murray CJL & GBD 2019 Risk Factors Collaborators* (Ginindza TG). Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet (2020); 396: 1223–49. https://doi.org/10.1016/S0140-6736(20)30752-2
  33. Lozano F, GBD 2019 Universal Health Coverage Collaborators* (Ginindza TG). Measuring UHC effective coverage index in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019. The Lancet (2020). https://doi.org/10.1016/S0140-6736(20)30750-9
  34. Deshpande A., Local Burden of Disease WaSH Collaborators* (Ginindza TG). Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17. Lancet Glob Health (2020); 8: e1162–85. https://doi.org/10.1016/S2214-109X(20)30278-3
  35. Mathias CT, Mianda S, Ginindza TG. Facilitating factors and barriers to accessibility and utilization of kangaroo mother care service among parents of low birth weight infants in Mangochi District, Malawi: A Qualitative study. BMC Pediatrics (2020) 20:355. https://doi.org/10.1186/s12887-020-02251-1
  36. Hlongwana K, Lubuzo B,  Phindile MlabaZondo S, Ginindza TG. Multistakeholder Experiences of Providing, Receiving, and Setting Priorities for Lung Cancer Care in KwaZulu-Natal Province, South Africa. American Society of Clinical Oncology JCO Global Oncol 2020:25., https://10.1200/GO.20.21000
  37. Wiens KE, Lindstedt PA, Blacker BF, Local Burden of Disease Diarrhoea Collaborators* (Ginindza TG). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17. The Lancet Global Health(2020)8(8): e1038-e1060. https://doi: 1016/S2214-109X(20)30230-8. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30230-8/fulltext
  38. Reiner RC, Local Burden of Disease Diarrhoea Collaborators*(Ginindza TG). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17. Lancet Glob Health 2020; 8: e1038–60. doi: https://doi.org/10.1016/S2214-109X(20)30230-8
  39. Lekoane KMB, Kuupiel D, Mashamba-Thompson TP, Ginindza TG. The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: scoping review. BMC: Systematic Reviews (2020) 9:88. https://doi.org/10.1186/s13643-020-01354-1
  40. Kahere M, Ginindza TG. Mapping evidence on the prevalence, incidence, risk factors and cost associated with chronic low back pain among adults in Sub-Saharan Africa: a systematic scoping review protocol. BMC Systematic Reviews (2020) 9:57 0) 9:57. https://doi.org/10.1186/s13643-020-01321-w
  41. Abbafati, C, GBD 2019 Diseases and Injuries Collaborators*(Ginindza TG). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet (2020); 396: 1204–22. https://doi.org/10.1016/S0140-6736(20)30925-9
  42. Abbafati, C, GBD 2019 Viewpoint Collaborators*(Ginindza TG). Five insights from the Global Burden of Disease Study 2019. Lancet (2020); 396: 1135–59. https://doi.org/10.1016/S0140-6736(20)31404-5
  43. Nwagbara UI, Ginindza TG, Hlongwana KW. Health systems influence on the pathways of care for lung cancer in low- and middle-income countries: a scoping review. Globalization and Health (2020) 16:23 https://doi.org/10.1186/s12992-020-00553-8
  44. Buhle Lubuzo, Ginindza TG, Hlongwana K. The barriers to initiating lung cancer care in low-and middle-income countries. Pan African Medical Journal. 2020; 35:38. https://doi.org/10.11604/pamj.2020.35.38.17333
  45. Ndlovu SR., Kuupiel D., Ginindza TG: Mapping evidence on the distribution of Paediatric cancers in sub-Saharan Africa: a scoping review protocol. BMC Systematic Reviews. (2019); (8)(262). https://doi.org/10.1186/s13643-019-1184-4
  46. Lubuzo B, Ginindza T, Hlongwana K. Exploring barriers to lung cancer patient access, diagnosis, referral and treatment in Kwazulu-Natal, South Africa: the health providers’ perspectives: TLCR journal; (2019) (8)(4). http://tlcr.amegroups.com/article/view/31039/21998
  47. Fitzmaurice Christina, GBD-Cancer Collaboration (Ginindza TG). Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 A Systematic Analysis for the Global Burden of Disease Study, JAMA Oncol. https://10.1001/jamaoncol.2019.2996
  48. GBD 2017 HIV collaborators (Ginindza TG). Global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. The Lancet HIV (2019). https://doi.org/10.1016/S2352-3018(19)30196-1
  49. Dlamini SB, Sartorius B, Ginindza T. Mapping the evidence on interventions to raise awareness on lung cancer in resource poor settings: a scoping review protocol: BMC Systematic Reviews; (2019); (8)(217) https://doi.org/10.1186/s13643-019-1138-x
  50. Lekoane BKM, Mashamba-Thompson TP, Ginindza TG. Evidence on the prevalence, incidence, mortality and trends of human papilloma virus-associated cancers in sub-Saharan Africa: systematic scoping review. BMC Cancer (2019); (19)(563). https://doi.org/10.1186/s12885-019-5781-3
  51. Chola M, Hlongwana K, Ginindza TG: Mapping Evidence on Decision-Making on Contraceptive Use Among Adolescents: A Scoping Review Protocol. Systematic Reviews (2018): (7)(201). https://doi.org/10.1186/s13643-018-0881-8
  52. Ginindza TG, Almonte M, Dlamin X, Sartorius B. Distribution of cervical abnormalities detected by visual inspection with acetic acid in Swaziland, 2011–2014: A retrospective study Afr J Prm Health Care Fam Med. (2018); (10)(1), a1773. https://phcfm.org/index.php/phcfm/article/view/1773/2856
  53. Ginindza TG, Sartorius B., Projected cervical Cancer incidence in Swaziland using three methods and local survey estimates BMC Cancer (2018); (18)(639). https://doi.org/10.1186/s12885-018-4540-1
  54. Mathias CT, Mianda S, Ginindza TG. Evidence of the factors that influence the utilization of Kangaroo Mother Care by parents with low birth weight infants in Low and Middle-Income Countries (LMICs): A scoping review protocol. BMC Systematic Reviews (2018) (7)55) https://doi.org/10.1186/s13643-018-0714-9
  55. Lekoane BKM, Mashamba-Thompson TP, Ginindza TG., Mapping evidence on the distribution of human papillomavirus-related cancers in sub-Saharan Africa: scoping review protocol BMC Systematic Reviews (2017) (6)(229). https://doi.org/10.1186/s13643-017-0623-3
  56. Ginindza TG, Dlamini X, Sartorius B, Östensson E. Cost analysis of Human Papillomavirus-related cervical diseases and genital warts in Swaziland. PLOS One Journal (2017), 12(5): e0177762. https://doi.org/10.1371/journal.pone.0177762
  57. Ginindza TG, Stefan CD, Tsoka-Gwegweni JM, Dlamini X, Jolly PE; Weiderpass E, Broutet N; Sartorius B. Prevalence and risk factors associated with sexually transmitted infections (STIs) among women of reproductive age in Swaziland. BMC-Infectious Agents and Cancer (2017) 12:29. https://doi.org/10.1186/s13027-017-0140-y.
  58. Ginindza TG, Dlamini X, Almonte M, Herrero R, Jolly P, Tsoka-Gwegweni JM, Weiderpass E, Broutet N, Sartorius B. Prevalence of and Associated Risk Factors for High Risk Human Papillomavirus among Sexually Active Women, Swaziland. PLOS One Journal (2017); 12(1) https://doi.org/10.1371/journal.pone.0170189
  59. Okwali M, Greenlee HGinindza T, Jolly P, Akinyemiju TF. Adherence to cancer prevention guidelines in South Africa is associated with health care access. Int Health (2016); 8(3) (211–219)https://doi.org/10.1093/inthealth/ihv044 .
  60. Zachariah, B. Mwagomba, D. Misinde, B.C. Mandere, A. Bemeyani, T. Ginindza, H. Cortier, K. Bissel, A. Jahnh, A.D. Harries. Vital registration in rural Africa: Is there a way forward to report on health targets of the Millennium Development Goals? Transactions of the Royal Society of Tropical Medicine and Hygiene (2011); (105) (6) (301–309). https://doi.org/10.1016/j.trstmh.2011.03.002
  61. Kalichman S.C, Simbayi L.C, Cloete A, Mthembu PP, Mkhonta R.N, Ginindza T. Measuring AIDS stigmas in people living with HIV/AIDS: The Internalized AIDS-Related Stigma Scale. AIDS Care Journal (2009); (2121) (1) (87–93). https://doi.org/10.1080/09540120802032627
  62. Maphalala G, Okello V, Mndzebele S, Gwebu P, Mulima N, Dlamini S, Nhlabatsi B, Ginindza T., et al (2008). Surveillance of transmitted HIV drug resistance in the Manzini-Mbabane Corridor, Swaziland, in 2006, Antiviral Therapy (2008) (13)(2)(95–100). https://doi.org/10.1177/135965350801302S12
  63. Whiteside A, Ginindza TG, Parikh A, Andrade C, Arrehag L, Dlamini, S. (2006). The Socio-Economic Impact of HIV/AIDS in Swaziland, http://www.gametlibrary.worldbank.org/FILES/1619 Socio-economic%20Impact%20of%20AIDS%20-%20Swaziland.pdf